Occupancy of the thiolation domain of the elongation module by a methylmalonyl moiety appears to trigger intermodular transfer of benzoate to the ketosynthase domain of the elongation module
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Therefore, the differential diagnosis between the two entities is based on the presence of a marked peripheral blood and alveolar eosinophilia in chronic eosinophilic pneumonia, and on histopathological analysis in organising pneumonia; however, pulmonary biopsy is rarely performed in chronic eosinophilic pneumonia 4
